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. 2019 Oct;164(10):2627-2630.
doi: 10.1007/s00705-019-04351-5. Epub 2019 Jul 30.

Genome characterization of the novel lytic Vibrio parahaemolyticus phage vB_VpP_BA6

Meiyan Yang  1   2 , Yongjian Liang  1   2 , Runbin Su  2 , Hanfang Chen  2 , Jing Wang  2 , Jumei Zhang  1 , Yu Ding  3 , Li Kong  1 , Haiyan Zeng  1 , Liang Xue  1 , Haoming Wu  1 , Qingping Wu  4
Affiliations

Genome characterization of the novel lytic Vibrio parahaemolyticus phage vB_VpP_BA6

Meiyan Yang et al. Arch Virol. 2019 Oct.

Abstract

A lytic bacteriophage, designated Vibrio phage vB_VpP_BA6, was isolated from sewage collected in Guangzhou, China. The double-stranded DNA genome of phage BA6 is composed of 50,520 bp with a G+C content of 41.77%. It possesses 64 open reading frames relating to phage structure, packaging, host lysis, DNA metabolism, and additional functions. Three tRNAs genes (encoding Pro, Ile and Trp) were detected. Comparison of its genomic features and phylogenetic analysis revealed that phage BA6 is a novel member of the family Podoviridae. This phage may represent a potential therapeutic agent against multidrug-resistant Vibrio parahaemolyticus.

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