Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Sep;32 Suppl 3(Suppl 3):29-33.

Possible clinical indications of ceftobiprole

J Barberán  1
Affiliations
Review

Possible clinical indications of ceftobiprole

J Barberán. Rev Esp Quimioter. 2019 Sep.

Abstract

Ceftobiprole is a fifth-generation cephalosporin approved for the treatment of adult community-acquired pneumonia and non-ventilator associated hospital-acquired pneumonia. However, its microbiological and pharmacokinetic profile is very attractive as armamentarium for empirical monotherapy treatment in other infections too. Among these, the following scenarios could be considered complicated skin and soft tissue infections, moderate-severe diabetic foot infections without bone involvement, vascular-catheter-associated-bloodstream infections, and fever without apparent focus in the hospitalized patient without septic shock or profound immunosuppression.

PubMed Disclaimer

References

    1. https://cima.aemps.es//cima/pdfs/es/ft/78691/78691_ft.pdf
    1. Pfaller MA, Flamm RK, Duncan LR, Streit JM, Castanheira M, Sader HS. Antimicrobial activity of ceftobiprole and comparator agents when tested against contemporary Gram-positive and-negative organisms collected from Europe (2015). Diagn Microbiol Infect Dis. 2018; 91(1):77-84. doi: 10.1016/j.diagmicrobio.2017.12.020. - DOI - PubMed
    1. Murthy B, Schmitt-Hoffmann A. Pharmacokinetics and pharmacodynamics of ceftobiprole, an anti-MRSA cephalosporin with broad-spectrum activity. Clin Pharmacokinet. 2008;47(1):21–33. DOI:10.2165/00003088-200847010-00003 - DOI - PubMed
    1. Moet GJ, Jones RN, Biedenbach DJ, Stilwell MG, Fritsche TR. Con-temporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY Antimicrobial Surveillance Program (1998–2004). Diagn Microbiol Infect Dis. 2007; 57:7–13. DOI:10.1016/j.diagmicrobio.2006.05.009 - DOI - PubMed
    1. Dryden MS. Complicated skin and soft tissue infection. J Antimicrob Chemother 2010; 65 (Suppl 3):iii35-44. doi:10.1093/jac/dkq302 - DOI - PubMed

MeSH terms