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. 2019 Aug 13;55(66):9837-9840.
doi: 10.1039/c9cc04550c.

Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base

Yuta Sadamitsu  1 , Akira Okumura, Kodai Saito, Tohru Yamada
Affiliations

Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base

Yuta Sadamitsu et al. Chem Commun (Camb). .

Abstract

The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atmosphere, nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.

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