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. 2019 Jul 29:52:e20180249.
doi: 10.1590/0037-8682-0249-2018.

Viral etiology of acute respiratory infections in children in Southern Iran

Mehrdad Halaji  1 , Tayebeh Hashempour  1 , Javad Moayedi  1 , Gholam Reza Pouladfar  1 , Behzad Khansarinejad  2 , Reza Khashei  3 , Afagh Moattari  3 , Zahra Musavi  1 , Farzaneh Ghassabi  1 , Neda Pirbonyeh  3
Affiliations
Free article

Viral etiology of acute respiratory infections in children in Southern Iran

Mehrdad Halaji et al. Rev Soc Bras Med Trop. .
Free article

Abstract

Introduction: Prevalence of influenza A virus (Flu-A), respiratory syncytial virus (RSV), and human metapneumovirus (hMPV) was assessed in children with acute respiratory infections (ARIs).

Methods: Nasopharyngeal aspirates and throat swabs were subjected to real-time polymerase chain reaction (PCR) to detect RSV and Flu-A and to conventional PCR to detect hMPV.

Results: Of the 156 children assessed, 93 (59.6%) carried at least one virus, with 35.9% positive for RSV, 14.1% for hMPV, and 9.6% for Flu-A. The prevalence of co-infections was 2.6%.

Conclusions: The high detection rate may reflect increased sensitivity of real-time PCR compared to traditional PCR and viral culture.

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