[Diagnosis and treatment of seven patients with brucellosis in non-pastoral areas]
- PMID: 31365982
- DOI: 10.3760/cma.j.issn.0578-1426.2019.08.009
[Diagnosis and treatment of seven patients with brucellosis in non-pastoral areas]
Abstract
To explore how to diagnose and treat brucellosis accurately and timely in patients with fever of unkown origin in non-pastoral areas. The epidemiological history, clinical symptoms, complete blood counts, procalcitonin and treatment efficacy of 7 patients with brucellosis were analyzed retrospectively. Some characteristic manifestations should be differentiated from tuberculosis. The clinical symptoms were relieved after combination of doxycycline, rifampicin, levofloxacin and amikacin for 6 weeks, only one patient with bone destruction needed orthopedic surgery. The overall response rate was 6/7. No relapse occurred during half year follow-up.
探讨非牧区"发热待查"患者中如何准确和迅速诊治布鲁菌病。对7例布鲁菌病患者的流行病学史、临床表现、血常规及降钙素原进行回顾性分析,发现有一定特征性改变,但需要与结核感染相鉴别。7例布鲁菌病患者经多西环素、利福平、左氧氟沙星、阿米卡星2~4种药物联合治疗6周,临床症状缓解,有1例患者有骨质破坏未愈,需要外科手术治疗,总有效率为6/7,所有患者治疗后半年随访均无复发。.
Keywords: Brucellosis; Non-pastoral areas; Tuberculosis infection.
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