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. 2019 Aug 1;58(8):596-598.
doi: 10.3760/cma.j.issn.0578-1426.2019.08.009.

[Diagnosis and treatment of seven patients with brucellosis in non-pastoral areas]

[Article in Chinese]
Affiliations

[Diagnosis and treatment of seven patients with brucellosis in non-pastoral areas]

[Article in Chinese]
M J Yuan et al. Zhonghua Nei Ke Za Zhi. .

Abstract

To explore how to diagnose and treat brucellosis accurately and timely in patients with fever of unkown origin in non-pastoral areas. The epidemiological history, clinical symptoms, complete blood counts, procalcitonin and treatment efficacy of 7 patients with brucellosis were analyzed retrospectively. Some characteristic manifestations should be differentiated from tuberculosis. The clinical symptoms were relieved after combination of doxycycline, rifampicin, levofloxacin and amikacin for 6 weeks, only one patient with bone destruction needed orthopedic surgery. The overall response rate was 6/7. No relapse occurred during half year follow-up.

探讨非牧区"发热待查"患者中如何准确和迅速诊治布鲁菌病。对7例布鲁菌病患者的流行病学史、临床表现、血常规及降钙素原进行回顾性分析,发现有一定特征性改变,但需要与结核感染相鉴别。7例布鲁菌病患者经多西环素、利福平、左氧氟沙星、阿米卡星2~4种药物联合治疗6周,临床症状缓解,有1例患者有骨质破坏未愈,需要外科手术治疗,总有效率为6/7,所有患者治疗后半年随访均无复发。.

Keywords: Brucellosis; Non-pastoral areas; Tuberculosis infection.

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