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Comment
. 2019 Aug;572(7767):E1-E2.
doi: 10.1038/s41586-019-1416-8. Epub 2019 Jul 31.

Do not discard Staphylococcus aureus WTA as a vaccine antigen

Rob van Dalen  1 , Michèle M Molendijk  1 , Sara Ali  2 , Kok P M van Kessel  1 , Piet Aerts  1 , Jos A G van Strijp  1 , Carla J C de Haas  1 , Jeroen Codée  2 , Nina M van Sorge  3
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Comment

Do not discard Staphylococcus aureus WTA as a vaccine antigen

Rob van Dalen et al. Nature. 2019 Aug.
No abstract available

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References

    1. Gerlach, D. et al. Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity. Nature 563, 705–709 (2018). - DOI
    1. Driguez, P. A. et al. Immunogenic compositions against S. aureus. WO patent WO/2017/064190 (2017).
    1. Xia, G. et al. Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM. J. Biol. Chem. 285, 13405–13415 (2010). - DOI
    1. Brown, S. et al. Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proc. Natl Acad. Sci. USA 109, 18909–18914 (2012). - DOI
    1. Brown, E. J. et al. Anti-wall teichoic antibodies and conjugates. WO patent WO/2014/194247 (2015).

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