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Review
. 2019 Jul-Aug;23(4):303-310.
doi: 10.4103/jisp.jisp_417_18.

Effect of scaling and root planing as monotherapy on glycemic control in patients of Type 2 diabetes with chronic periodontitis: A systematic review and meta-analysis

Akanksha Jain  1 , Jyoti Gupta  1 , Dipika Bansal  2 , Shaveta Sood  1 , Shipra Gupta  1 , Ashish Jain  1
Affiliations
Review

Effect of scaling and root planing as monotherapy on glycemic control in patients of Type 2 diabetes with chronic periodontitis: A systematic review and meta-analysis

Akanksha Jain et al. J Indian Soc Periodontol. 2019 Jul-Aug.

Abstract

Background: There is enough evidence, which suggests that nonsurgical periodontal therapy (NSPT) improved the glycemic control in patients of Type 2 diabetes mellitus (T2DM) with chronic periodontitis (CP). This meta-analysis is aimed to explore the effect of NSPT, exclusively scaling and root planing (SRP) as monotherapy on glycemic control and periodontal parameters in patients of T2DM with CP.

Materials and methods: Two databases, MEDLINE and EMBASE, were searched from June 2006 to June 2016. Initially, 464 potentially relevant studies were evaluated. Randomized controlled trials with duration of ≥3 months, based on the treatment group managed with SRP without any supportive use of local drug delivery or systemic antibiotics, while the control group received no periodontal therapy, were selected. This resulted in six appropriate articles with a total of 812 patients of T2DM with CP. Alteration in glycated hemoglobin (HbA1c) was the primary outcome measure, whereas the changes in clinical attachment level (CAL) and probing pocket depth (PPD) were the secondary outcome measures.

Results: SRP treatment resulted in a decrease in HbA1c by 0.26% (P = 0.17) at 3-4 months compared to the control group. Further, on subgroup analysis, SRP therapy revealed a decrease in PPD and CAL at 3-4 months, though statistically insignificant.

Conclusion: SRP treatment leads to modest improvement in glycemic status and periodontal parameters in T2DM patients with CP at 3-4 months.

Keywords: Chronic periodontitis; Type 2 diabetes mellitus; clinical attachment level; glycated hemoglobin; meta-analysis; probing pocket depth; scaling and root planning; systematic review.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Flow diagram representing the selection process (T1DM* – Type 1 diabetes mellitus, IGT* – Impaired glucose tolerance). n – Number of articles
Figure 2
Figure 2
Percentages of risk of bias items across all included studies
Figure 3
Figure 3
Forest plot showing change in glycated hemoglobin (%) at 3-month. SD – Standard deviation; IV – Intravitreal; CI – Confidence interval
Figure 4
Figure 4
Funnel plot assessing the publication bias
Figure 5
Figure 5
Forest plot showing alterations in probing pocket depth (mm) from baseline to 3 months. SD – Standard deviation; IV – Intravitreal; CI – Confidence interval
Figure 6
Figure 6
Forest plot showing change in clinical attachment level (mm) from baseline to 3-month. SD – Standard deviation; IV – Intravitreal; CI – Confidence interval
See this image and copyright information in PMC

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