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Review
. 2019 Oct;26(5):256-265.
doi: 10.1097/MED.0000000000000500.

Thyroid disease and the metabolic syndrome

Ladan Mehran  1 , Atieh Amouzegar, Fereidoun Azizi
Affiliations
Review

Thyroid disease and the metabolic syndrome

Ladan Mehran et al. Curr Opin Endocrinol Diabetes Obes. 2019 Oct.

Abstract

Purpose of review: To summarize recent developments in the association of thyroid function with metabolic syndrome (MetS).

Recent findings: Although thyroid hormones even within low normal range are associated with various metabolic abnormalities, the risk of MetS remains a controversial issue. Hyperthyroid state might be associated only with insulin resistance and dysglycemia. Autoimmune thyroid diseases may be a potential risk factor for metabolic abnormalities even in those with low normal thyroid function.

Summary: The interrelation between thyroid stimulating hormone, free T3, freeT4 and metabolic parameters is complex and might be affected by age, sex, BMI, insulin resistance, smoking, iodine intake and inflammatory markers.

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