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Comment
. 2019 Aug 2;365(6452):440-441.
doi: 10.1126/science.aay2859.

Cancer cell evolution through the ages

Carlo C Maley  1 , Darryl Shibata  2
Affiliations
Comment

Cancer cell evolution through the ages

Carlo C Maley et al. Science. .
No abstract available

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Figures

None
The evolution of transmissible tumors in dogs
Canine transmissible venereal tumor (CTVT) arose in a normal dog ~6000 years ago in Asia. The five driver mutations identified in CTVTs today were likely present in the first CTVT cell. CTVT evolution has been neutral for most of its history, accumulating large numbers of passenger mutations.
See this image and copyright information in PMC

Comment on

  • Somatic evolution and global expansion of an ancient transmissible cancer lineage.
    Baez-Ortega A, Gori K, Strakova A, Allen JL, Allum KM, Bansse-Issa L, Bhutia TN, Bisson JL, Briceño C, Castillo Domracheva A, Corrigan AM, Cran HR, Crawford JT, Davis E, de Castro KF, B de Nardi A, de Vos AP, Delgadillo Keenan L, Donelan EM, Espinoza Huerta AR, Faramade IA, Fazil M, Fotopoulou E, Fruean SN, Gallardo-Arrieta F, Glebova O, Gouletsou PG, Häfelin Manrique RF, Henriques JJGP, Horta RS, Ignatenko N, Kane Y, King C, Koenig D, Krupa A, Kruzeniski SJ, Kwon YM, Lanza-Perea M, Lazyan M, Lopez Quintana AM, Losfelt T, Marino G, Martínez Castañeda S, Martínez-López MF, Meyer M, Migneco EJ, Nakanwagi B, Neal KB, Neunzig W, Ní Leathlobhair M, Nixon SJ, Ortega-Pacheco A, Pedraza-Ordoñez F, Peleteiro MC, Polak K, Pye RJ, Reece JF, Rojas Gutierrez J, Sadia H, Schmeling SK, Shamanova O, Sherlock AG, Stammnitz M, Steenland-Smit AE, Svitich A, Tapia Martínez LJ, Thoya Ngoka I, Torres CG, Tudor EM, van der Wel MG, Viţălaru BA, Vural SA, Walkinton O, Wang J, Wehrle-Martinez AS, Widdowson SAE, Stratton MR, Alexandrov LB, Martincorena I, Murchison EP. Baez-Ortega A, et al. Science. 2019 Aug 2;365(6452):eaau9923. doi: 10.1126/science.aau9923. Science. 2019. PMID: 31371581 Free PMC article.

References

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