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. 1988 Sep;56(9):2512-4.
doi: 10.1128/iai.56.9.2512-2514.1988.

Induced engulfment of Neisseria gonorrhoeae by tissue culture cells

W P Richardson  1 , J C Sadoff
Affiliations

Induced engulfment of Neisseria gonorrhoeae by tissue culture cells

W P Richardson et al. Infect Immun. 1988 Sep.

Abstract

Engulfment of gonococci by mammalian tissue culture cells was examined as a model of the penetration of host cells in gonorrhea. Engulfment required viable organisms; killing the gonococci with heat or refrigeration abolished the process. Engulfment also required tissue culture cell microtubule- and microfilament-dependent movement; treating the cells with cytochalasin B (0.5 micrograms/ml) or demecolcine (Colcemid; Ciba-Geigy AG, Basel, Switzerland) (10 micrograms/ml) also prevented his process.

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References

    1. J Med Microbiol. 1973 Aug;6(3):399-403 - PubMed
    1. Br J Vener Dis. 1973 Oct;49(5):435-40 - PubMed
    1. Infect Immun. 1988 Jun;56(6):1625-32 - PubMed
    1. J Cell Biol. 1977 Dec;75(3):666-93 - PubMed
    1. Infect Immun. 1986 Oct;54(1):154-60 - PubMed

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