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Editorial
. 2019 Jun;11(6):2195-2197.
doi: 10.21037/jtd.2019.05.72.

Does this recent randomised controlled trial of intermittent pneumatic compression devices really indicate that they are ineffective in critical care patients?

Martin Dennis  1
Affiliations
Editorial

Does this recent randomised controlled trial of intermittent pneumatic compression devices really indicate that they are ineffective in critical care patients?

Martin Dennis. J Thorac Dis. 2019 Jun.
No abstract available

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Conflict of interest statement

Conflicts of Interest: M Dennis received departmental funding from the National Institute for Health Research Health Technology Assessment Boards to run the CLOTS 3 trial. Covidien provided compression equipment to the sites participating in the trial. M Dennis has no personal interest in Covidien and has never accepted any funding, grants or speakers fees from them.

Comment on

  • Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis.
    Arabi YM, Al-Hameed F, Burns KEA, Mehta S, Alsolamy SJ, Alshahrani MS, Mandourah Y, Almekhlafi GA, Almaani M, Al Bshabshe A, Finfer S, Arshad Z, Khalid I, Mehta Y, Gaur A, Hawa H, Buscher H, Lababidi H, Al Aithan A, Abdukahil SAI, Jose J, Afesh LY, Al-Dawood A; Saudi Critical Care Trials Group. Arabi YM, et al. N Engl J Med. 2019 Apr 4;380(14):1305-1315. doi: 10.1056/NEJMoa1816150. Epub 2019 Feb 18. N Engl J Med. 2019. PMID: 30779530 Clinical Trial.

References

    1. Arabi YM, Al-Hameed F, Burns KEA, et al. Adjunctive intermittent pneumatic compression for venous thromboprophylaxis. N Engl J Med 2019;380:1305-15. 10.1056/NEJMoa1816150 - DOI - PubMed
    1. CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration, Dennis M, Sandercock P, et al. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet 2013;382:516-24. 10.1016/S0140-6736(13)61050-8 - DOI - PubMed
    1. Warlow C, Ogston D, Douglas AS. Deep venous thrombosis of the legs after strokes. Br Med J 1976;1:1178-81. 10.1136/bmj.1.6019.1178 - DOI - PMC - PubMed
    1. Dennis M, Mordi N, Graham C, et al. The timing, extent, progression and regression of DVT in immobile stroke patients: observational data from the CLOTS randomized trials. J Thromb Haemost 2011;9:2193-200. 10.1111/j.1538-7836.2011.04486.x - DOI - PubMed
    1. Sandercock PA, Counsell C, Kane EJ. Anticoagulants for acute ischaemic stroke. Cochrane Database Syst Rev 2015;(3):CD000024. - PMC - PubMed