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Published Erratum
. 2019 Aug 1;105(2):441-442.
doi: 10.1016/j.ajhg.2019.07.009.

Genes for Good: Engaging the Public in Genetics Research via Social Media

Katharine Brieger, Gregory J M Zajac, Anita Pandit, Johanna R Foerster, Kevin W Li, Aubrey C Annis, Ellen M Schmidt, Chris P Clark, Karly McMorrow, Wei Zhou, Jingjing Yang, Alan M Kwong, Andrew P Boughton, Jinxi Wu, Chris Scheller, Tanvi Parikh, Alejandro de la Vega, David M Brazel, Maia Frieser, Gianna Rea-Sandin, Lars G Fritsche, Scott I Vrieze, Gonçalo R Abecasis
Published Erratum

Genes for Good: Engaging the Public in Genetics Research via Social Media

Katharine Brieger et al. Am J Hum Genet. .
No abstract available

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Figures

Figure 3
Figure 3
Eye Color Distribution Distribution of eye color among participants with different genotypes at rs12913832 (the top signal when performing GWAS using blue eye color in Genes for Good participants), a marker in HERC2 known to play a role in eye color determination.
Figure 4
Figure 4
Effect Size Estimates of a GWAS for BMI in Our Study Sample Compared to Findings from a Meta-analysis We compare effect estimates from Genes for Good to published findings from the Locke et al. meta-analysis of BMI GWAS.24 Specifically, we looked at the top ten reported signals and were able to replicate all of these effects in direction and nominal significance (p < 0.05). The forest plot on the right compares effect size estimates across studies; the dashed lines represent the confidence intervals around the Genes for Good estimates, while the solid lines represent results from Locke et al. Given the relatively small sample size available in this data freeze, our estimates have fairly wide confidence limits. However, Locke’s estimates are completely contained within our limits for eight of ten SNPs. Asterisk indicates imputed variant.
See this image and copyright information in PMC

Erratum for

  • Genes for Good: Engaging the Public in Genetics Research via Social Media.
    Brieger K, Zajac GJM, Pandit A, Foerster JR, Li KW, Annis AC, Schmidt EM, Clark CP, McMorrow K, Zhou W, Yang J, Kwong AM, Boughton AP, Wu J, Scheller C, Parikh T, de la Vega A, Brazel DM, Frieser M, Rea-Sandin G, Fritsche LG, Vrieze SI, Abecasis GR. Brieger K, et al. Am J Hum Genet. 2019 Jul 3;105(1):65-77. doi: 10.1016/j.ajhg.2019.05.006. Epub 2019 Jun 13. Am J Hum Genet. 2019. PMID: 31204010 Free PMC article.

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