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Review
. 2019 Nov:78:100-108.
doi: 10.1016/j.ijdevneu.2019.07.010. Epub 2019 Jul 30.

Neglect, HPA axis reactivity, and development

Emily B Reilly  1 , Megan R Gunnar  1
Affiliations
Review

Neglect, HPA axis reactivity, and development

Emily B Reilly et al. Int J Dev Neurosci. 2019 Nov.

Abstract

Neglect is a common and frequently chronic form of child maltreatment that can compromise child development and increase the risk of physical and psychological problems. In this review, we discuss one of the potential ways neglect becomes biologically embedded by shaping the development of a key stress responsive system: namely, the hypothalamic-pituitary-adrenal (HPA) axis. Several potential mediators and moderators of this process are examined, including inflammation, attachment and social buffering, self-regulation, child sex and age, and genetics.

Keywords: Child development; HPA axis; Neglect.

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References

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MeSH terms