Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Aug 1;9(3):39.
doi: 10.3390/jpm9030039.

Omics Meeting Onics: Towards the Next Generation of Spectroscopic-Based Technologies in Personalized Medicine

Weng Kung Peng  1 , Daniele Paesani  2
Affiliations
Editorial

Omics Meeting Onics: Towards the Next Generation of Spectroscopic-Based Technologies in Personalized Medicine

Weng Kung Peng et al. J Pers Med. .

Abstract

This article aims to discuss the recent development of integrated point-of-care spectroscopic-based technologies that are paving the way for the next generation of diagnostic monitoring technologies in personalized medicine. Focusing on the nuclear magnetic resonance (NMR) technologies as the leading example, we discuss the emergence of -onics technologies (e.g., photonics and electronics) and how their coexistence with -omics technologies (e.g., genomics, proteomics, and metabolomics) can potentially change the future technological landscape of personalized medicine. The idea of an open-source (e.g., hardware and software) movement is discussed, and we argue that technology democratization will not only promote the dissemination of knowledge and inspire new applications, but it will also increase the speed of field implementation.

Keywords: decentralization; personalized medicine; spectroscopic-based technologies; technology democratization.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Electromagnetic spectrum with respect to the impedance spectroscopy used (e.g., nuclear magnetic resonance (NMR), electron spin resonance (ESR), and THz spectroscopy) to develop the next generation of integrated PoC spectroscopic-based technologies in personalized medicine.
Figure 2
Figure 2
A simplified block diagram of the architecture of a software based radio (SDR)-based NMR spectrometer showing the separation of digital and analogue sections. The glossary is as follows: pulse programmer (PPG), receiver (RCVR), transmitter (TRANS), analog-digital converter (ADC), digital-analog converter (DAC), power amplifier (PA), preamplifier (p-amp), radio frequency (rf), and universal serial bus (USB).
See this image and copyright information in PMC

References

    1. Urnov F.D. A path to efficient gene editing. Nat. Med. 2018;24:899–900. doi: 10.1038/s41591-018-0110-y. - DOI - PubMed
    1. Larochelle S. CRISPR—Cas goes RNA. Nat. Methods. 2018;15:312. doi: 10.1038/nmeth.4681. - DOI
    1. Van Steensel B., Furlong E.E.M. The role of transcription in shaping the spatial organization of the genome. Nat. Rev. Mol. Cell Boil. 2019;20:327–337. doi: 10.1038/s41580-019-0114-6. - DOI - PMC - PubMed
    1. Rowley M.J., Corces V.G. Organizational principles of 3D genome architecture. Nat. Rev. Genet. 2018;19:789–800. doi: 10.1038/s41576-018-0060-8. - DOI - PMC - PubMed
    1. Chiasson M., Fowler D.M. Mutagenesis-based protein structure determination. Nat. Genet. 2019;51:1072–1073. doi: 10.1038/s41588-019-0461-4. - DOI - PubMed

Publication types

LinkOut - more resources