Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2019 Oct;161(10):2073-2082.
doi: 10.1007/s00701-019-04021-0. Epub 2019 Aug 3.

Ultrasonic aspiration in neurosurgery: comparative analysis of complications and outcome for three commonly used models

Stephanie Henzi  1   2 , Niklaus Krayenbühl  1   2 , Oliver Bozinov  1   2 , Luca Regli  1   2 , Martin N Stienen  3   4
Affiliations
Comparative Study

Ultrasonic aspiration in neurosurgery: comparative analysis of complications and outcome for three commonly used models

Stephanie Henzi et al. Acta Neurochir (Wien). 2019 Oct.

Abstract

Introduction: Ultrasonic aspiration (UA) devices are commonly used for resecting intracranial tumors, as they allow for internal debulking of large tumors, hereby avoiding damage to adjacent brain tissue during the dissection. Little is known about their comparative safety profiles.

Methods and materials: We analyzed data from a prospective patient registry. Procedures using one of the following UA models were included: Integra® CUSA, Söring®, and Stryker® Sonopet. The primary endpoint was morbidity at discharge, defined as significant worsening on the Karnofsky Performance Scale. Secondary endpoints included morbidity and mortality until 3 months postoperative (M3), occurrence, type, and etiology of complications.

Results: Of n = 1028 procedures, the CUSA was used in n = 354 (34.4 %), the Söring in n = 461 (44.8 %), and the Sonopet in n = 213 (20.7 %). There was some heterogeneity of study groups. In multivariable analysis, patients in the Söring (adjusted odds ratio (aOR) 1.29; 95 % confidence interval (CI), 0.80-2.08; p = 0.299), and Sonopet group (aOR, 0.86; 95 % CI, 0.46-1.61; p = 0.645) were as likely as patients in the CUSA group to experience discharge morbidity. At M3, patients in the Söring (aOR, 1.20; 95 % CI, 0.78-1.86; p = 0.415) and Sonopet group (aOR, 0.53; 95 % CI, 0.26-1.08; p = 0.080) were as likely as patients in the CUSA group to experience morbidity. There were also no differences for M3 morbidity in subgroup analyses for gliomas, meningiomas, and metastases. The grade (p = 0.608) and etiology (p = 0.849) of postoperative complications were similar.

Conclusions: Neurosurgeons select UA types with regard to certain case-specific characteristics. The safety profiles of three commonly used UA types appear mostly similar.

Keywords: Complications; Intracranial tumor; Morbidity; Mortality; Outcome; Ultrasonic aspiration.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Algorithm describing how the study arrived at the final cohort size at baseline and follow-up 3 months postoperative (M3)
See this image and copyright information in PMC

References

    1. Ahn A, Phan K, Cheung ZB, White SJW, Kim JS, Cho SK. Predictors of discharge disposition following laminectomy for intradural extramedullary spinal tumors. World Neurosurg. 2018;123:e427–e432. doi: 10.1016/j.wneu.2018.11.183. - DOI - PubMed
    1. Awad A, Bader-El-Den M, McNicholas J. Patient length of stay and mortality prediction: a survey. Health Serv Manag Res. 2017;30:105–120. doi: 10.1177/0951484817696212. - DOI - PubMed
    1. Baddour HM, Lupa MD, Patel ZM. Comparing use of the Sonopet((R)) ultrasonic bone aspirator to traditional instrumentation during the endoscopic transsphenoidal approach in pituitary tumor resection. Int Forum Allergy Rhinol. 2013;3:588–591. doi: 10.1002/alr.21143. - DOI - PubMed
    1. Brock M, Ingwersen I, Roggendorf W. Ultrasonic aspiration in neurosurgery. Neurosurg Rev. 1984;7:173–177. doi: 10.1007/BF01780701. - DOI - PubMed
    1. Cinalli G, Imperato A, Mirone G, Di Martino G, Nicosia G, Ruggiero C, Aliberti F, Spennato P. Initial experience with endoscopic ultrasonic aspirator in purely neuroendoscopic removal of intraventricular tumors. J Neurosurg Pediatr. 2017;19:325–332. doi: 10.3171/2016.10.PEDS16352. - DOI - PubMed

Publication types