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Case Reports
. 2019 Jul 14:2019:6821854.
doi: 10.1155/2019/6821854. eCollection 2019.

Multiple Nonfamilial Unilateral Trichoepitheliomas: Report of a Case-Mini Review of the Literature

I Mandekou-Lefaki  1 , G Theodosiou  2 , F-S Delli  3 , D Oikonomou  4 , M Papageorgiou  3
Affiliations
Case Reports

Multiple Nonfamilial Unilateral Trichoepitheliomas: Report of a Case-Mini Review of the Literature

I Mandekou-Lefaki et al. Case Rep Dermatol Med. .

Abstract

Trichoepitheliomas are benign skin tumors with follicular differentiation that present most commonly as solitary lesions. They can also present as multiple centrofacial papules due to several mutations in the CYLD gene. Multiple unilateral trichoepitheliomas in a linear or dermatomal distribution may rarely be seen. Herein, we report a case of multiple unilateral trichoepitheliomas on the face of a healthy 34-year-old woman of Caucasian origin.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Numerous skin-colored papules on the right side of the patient's face. (b) The left side of the face is free of lesions. (c) Closer view of the right side: multiple rounded whitish and skin-colored papules and nodules symmetrically distributed on the lower eyelid and the perinasal area.
Figure 2
Figure 2
Polarized contact dermatoscopy: on a white-ivory background, bright white lines and yellow to light brown dots and clods.
Figure 3
Figure 3
Histopathology: hematoxylin and eosin stain; original magnification x40: multiple horn cysts and aggregations of basaloid keratinocytes surrounded by a fibrous stroma.
Figure 4
Figure 4
Marked improvement after a 3-month treatment with cream imiquimod 5%.
See this image and copyright information in PMC

References

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