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Comment
. 2019 Aug 5:366:l4479.
doi: 10.1136/bmj.l4479.

Unmasking the vulnerabilities of uninfected children exposed to HIV

Vundli Ramokolo  1 , Ameena E Goga  2   3   4 , Amy L Slogrove  5 , Kathleen M Powis  6   7   8
Affiliations
Comment

Unmasking the vulnerabilities of uninfected children exposed to HIV

Vundli Ramokolo et al. BMJ. .

Abstract

Although programmes to reduce vertical transmission of HIV mean fewer children are acquiring HIV, more needs to be done to understand the longer term outcomes of exposure, say Vundli Ramokolo and colleagues

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Conflict of interest statement

Competing interests: We have read and understood BMJ policy on declaration of interests and declare no competing interests. This article was funded by the South African Medical Research Council and Unicef. Research reported in this publication was also supported by the Fogarty International Center of the National Institutes of Health under Award Number 1K43TW010683 to ALS and the Eunice Kennedy Shriver National Institute of Child Health and Human Development under Award Number 1R21HD093531 to KMP. ALS receives salary support through the CIPHER Grantee Programme of the International AIDS Society (2017/518-SLO) while VR receives support from the SAMRC Intramural Postdoctoral Fellowship Programme. The content of this paper is the sole responsibility of the authors and does not necessarily represent the official views of the organisations and funders.

Figures

Fig 1
Fig 1
UNAIDS estimates of the number of uninfected children exposed to HIV in South Africa. Solid line represents the point estimate with the uncertainty bounds in the shaded area
See this image and copyright information in PMC

Comment on

References

    1. UNAIDS. Number of HIV-exposed children who are uninfected. 2018 http://aidsinfo.unaids.org/
    1. World Health Organization Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection—recommendations for a public health approach. 2nd ed World Health Organization, 2016. - PubMed
    1. Evans C, Jones CE, Prendergast AJ. HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination. Lancet Infect Dis 2016;16:e92-107. 10.1016/S1473-3099(16)00055-4 - DOI - PubMed
    1. Slogrove AL, Johnson LFP, Powis KM. Population-level mortality associated with HIV exposure in HIV-uninfected infants in Botswana and South Africa: a model-based evaluation. J Trop Pediatr 2018. [Epub ahead of print.] - PMC - PubMed
    1. Evans C, Humphrey JH, Ntozini R, Prendergast AJ. HIV-exposed uninfected infants in Zimbabwe: insights into health outcomes in the pre-antiretroviral therapy era. Front Immunol 2016;7:190. 10.3389/fimmu.2016.00190 - DOI - PMC - PubMed

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