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Case Reports
. 2019 Jun 10;32(3):377-378.
doi: 10.1080/08998280.2019.1613331. eCollection 2019 Jul.

Hydralazine-induced pericardial effusion

Mohammed Faisal Rahman  1 , Muhammad Ajmal Panezai  1 , Harold M Szerlip  1
Affiliations
Case Reports

Hydralazine-induced pericardial effusion

Mohammed Faisal Rahman et al. Proc (Bayl Univ Med Cent). .

Abstract

Drug-induced lupus (DIL) is due to an autoimmune reaction to a drug with an estimated incidence of 15,000 to 30,000 cases every year in the US. Hydralazine is a well-known offender. Antinuclear antibody (ANA) is present in most cases, though four cases of ANA-negative DIL have been reported. In this report, we present another case of ANA-negative DIL secondary to hydralazine.

Keywords: ANA-negative drug-induced lupus; hydralazine-induced lupus; pericardial effusion.

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Figures

Figure 1.
Figure 1.
(a) Chest x-ray showing marked enlargement of the cardiac silhouette. (b) Echocardiography showing large pericardial effusion (arrow).
See this image and copyright information in PMC

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