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Review
. 2019 Jul 25:10:2042018819865399.
doi: 10.1177/2042018819865399. eCollection 2019.

The road from intermittently scanned glucose monitoring to hybrid closed-loop systems: Part A. Keys to success: subject profiles, choice of systems, education

Francesca De Ridder  1 , Marieke den Brinker  2 , Christophe De Block  3
Affiliations
Review

The road from intermittently scanned glucose monitoring to hybrid closed-loop systems: Part A. Keys to success: subject profiles, choice of systems, education

Francesca De Ridder et al. Ther Adv Endocrinol Metab. .

Abstract

Managing type 1 diabetes (T1DM) is challenging and requires intensive glucose monitoring and titration of insulin in order to reduce the risk of complications. The use of continuous glucose monitoring (CGM) systems, either flash or intermittently scanned glucose monitoring (isCGM) or real-time (RT) CGM, has positively affected the management of type 1 diabetes with the potential to lower HbA1c, enhance time spent in range, reduce frequency and time spent in hypoglycemia and hyperglycemia, lower glycemic variability, and improve quality of life. In recent years, both CGM and pump technology have advanced, with improved functional features and integration, including low glucose suspend (LGS), predictive low glucose suspend (PLGS), and hybrid closed-loop (HCL) systems. In this review, we highlight the benefits and limitations of use of isCGM/RT-CGM for open-loop control and recent progress in closed-loop control systems. We also discuss different subject profiles for the different systems, and focus on educational aspects that are key to successful use of the systems.

Keywords: continuous glucose monitoring; diabetes education; diabetes mellitus; hybrid closed loop; intermittently scanned glucose monitoring.

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Conflict of interest statement

Conflict of interest statement: CDB is a consultant for Abbott, A. Menarini Diagnostics, Lilly, Medtronic, Novo Nordisk, and Roche Diagnostics. The other authors have no conflicts of interest to declare.

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