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Review
. 2020 Jan;49(1):9-13.
doi: 10.1111/jop.12943. Epub 2019 Aug 22.

A review of recent advances in histopathological assessment of head and neck squamous cell carcinoma

Soudeh Chegini  1 , Konstantinos Mitsimponas  2 , Kaveh Shakib  3
Affiliations
Review

A review of recent advances in histopathological assessment of head and neck squamous cell carcinoma

Soudeh Chegini et al. J Oral Pathol Med. 2020 Jan.

Abstract

Squamous cell carcinoma (SCC) is the most common non-cutaneous head and neck (H&N) malignancy. Referrals for suspected SCC are seen by oral and maxillofacial surgery (OMFS) surgeons and represent the bulk of 2-week wait referrals. The diagnosis and treatment of SCC is heavily influenced by national and international guidelines. The majority of research and funding is directed towards this condition. This has led to continuous changes to update these guidelines. However, there remain areas of controversy and conflicting evidence. This article summarises articles pertinent to pathologists between 2016 and 2018 published in the leading British OMFS journal. A total of 22 published articles relating to the histopathology of non-cutaneous H&N SCC were selected.

Keywords: H&N SCC; TNM classification; diagnosis; resection margin; sentinel node.

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References

REFERENCES

    1. Kennedy RA. WHO is in and WHO is out of the mouth, salivary glands, and jaws sections of the 4th edition of the WHO classification of head and neck tumours. Br J Oral Maxillofac Surg. 2018;56(2):90-95.
    1. Vuity D, McMahon J, Takhiuddin S, et al. Is the 8th edition of the Union for International Cancer Control staging of oral cancer good enough? Br J Oral Maxillofac Surg. 2018;56(4):272-277.
    1. Barrett AW, Tighe JV, Gulati A, et al. Staging of squamous cell carcinoma of the tongue: extrinsic lingual muscles and the 8th editions of the American Joint Committee on Cancer/Union for International Cancer Control staging manuals. Br J Oral Maxillofac Surg. 2017;55(9):921-926.
    1. Murakami R, Nakayama H, Semba A, et al. Prognostic impact of the level of nodal involvement: retrospective analysis of patients with advanced oral squamous cell carcinoma. Br J Oral Maxillofac Surg. 2017;55(1):50-55.
    1. Goodson ML, Sloan P, Robinson CM, Cocks K, Thomson PJ. Oral precursor lesions and malignant transformation-who, where, what, and when? Br J Oral Maxillofac Surg. 2015;53(9):831-835.

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