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Editorial
. 2019 Aug 6;11(15):5298-5299.
doi: 10.18632/aging.102147. Epub 2019 Aug 6.

The risk of jiggly fat in aging

Patricia Corrales  1 , Marina Martín-Taboada  1 , Gema Medina-Gomez  1
Affiliations
Editorial

The risk of jiggly fat in aging

Patricia Corrales et al. Aging (Albany NY). .
No abstract available

Keywords: adipose tissue; aging; caloric restriction; insulin resistance.

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Figures

Figure 1
Figure 1
Altered processes in Subcutaneous WAT during the first stages of aging. Subcutaneous WAT (scWAT) shows a defect in hypertrophy and/or hyperplasia, fibrosis and inflammatory processes and insulin resistance (IR) appears progressively in this tissue during the first stages of aging. Insulin receptor substrate (IRS), phosphoinositol-3-kinase (PI3K), glucose transporter (GLUT), c-Jun kinases (JNK), protein kinase B (PKB or AKT), phosphatidylinositol (3,4,5)-tris- phosphate (PIP3), phosphatidylinositol 4,5-bisphosphate (PIP2), free fatty acids (FFA) and diacylglycerol (DAG).
See this image and copyright information in PMC

References

    1. Redman LM, et al. Cell Metab. 2018; 27:805–815.e4. 10.1016/j.cmet.2018.02.019 - DOI - PMC - PubMed
    1. Sierra Rojas JX, et al. J Gerontol A Biol Sci Med Sci. 2016; 71:310–22. 10.1093/gerona/glv117 - DOI - PubMed
    1. Escrivá F, et al. J Endocrinol. 2007; 194:131–41. 10.1677/joe.1.07043 - DOI - PubMed
    1. Corrales P, et al. Aging Cell. 2019; 18:e12948. 10.1111/acel.12948 - DOI - PMC - PubMed
    1. Boden G, Shulman GI. Eur J Clin Invest. 2002. (Suppl 3); 32:14–23. 10.1046/j.1365-2362.32.s3.3.x - DOI - PubMed

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