Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Aug 6;14(8):e0220605.
doi: 10.1371/journal.pone.0220605. eCollection 2019.

Gap analysis for drug development policy-making: An attempt to close the gap between policy and its implementation

Ria Christine Siagian  1 , Dumilah Ayuningtyas  1
Affiliations

Gap analysis for drug development policy-making: An attempt to close the gap between policy and its implementation

Ria Christine Siagian et al. PLoS One. .

Abstract

Introduction: Most drug development policies in developing countries are enacted without achieving the desired results. This study aims to determine the prioritization of drug development in Indonesia through the evidence-based policymaking process in order to close the distance between stated policy goals and the realization of planned goals.

Methods: A quantitative approach in the form of cross-sectional research using a structured survey was adopted and validated using a set of techniques involved in the calculation of a structural equation model. An independent samples t-test was used to test the significance of the differences between two views: pharmaceutical industries and the government of Indonesia.

Findings: The study reveals that pharmaceutical industries and governments were highly consistent in their perceived challenges in facing the drug development. It also reveals drivers and weaknesses of drug development, including market opportunities, push-pull-regulatory pull factors and regulation, as priorities for improvement.

Conclusions: Gap analysis based on a structural model was borne out to address gap challenges between policy and its implementation, with the use of evidence-based policymaking.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Conceptual model.
Fig 2
Fig 2. Final performance model.
Fig 3
Fig 3. Final potential situation model.
Fig 4
Fig 4. Importance—Performance map for current performance (left) and potential situation (right).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Kamoru Ahmed I. Problems and Challenges of Policy Implementation for National Development. 2016;6: 2225–0484.
    1. Hennink M, Stephenson R. Using research to inform health policy: Barriers and strategies in developing countries. J Health Commun. 2005;10: 163–180. 10.1080/10810730590915128 - DOI - PubMed
    1. Saguin K. Policy consulting in developing countries: evidence from the Philippines. J Asian Public Policy. 2018;11: 188–205.
    1. Da Costa O, Warnke P, Cagnin C, Scapolo F. The impact of foresight on policy-making: Insights from the FORLEARN mutual learning process. Technol Anal Strateg Manag. 2008;20: 369–387.
    1. Weiss B, Pollack AA. Barriers to global health development: An international quantitative survey. PLoS One. 2017;12: 1–23. - PMC - PubMed

Publication types