Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Oct;42(5):324-333.
doi: 10.1002/nur.21977. Epub 2019 Aug 7.

Feasibility of an intervention for men on androgen deprivation therapy: A research protocol

Affiliations

Feasibility of an intervention for men on androgen deprivation therapy: A research protocol

Alana Manson et al. Res Nurs Health. 2019 Oct.

Abstract

Androgen deprivation therapy (ADT) is a treatment used across the prostate cancer disease spectrum and works by suppressing testicular androgen production to castrate levels. Although ADT can provide survival benefits, it is also associated with increased risk for cardiovascular disease, metabolic syndrome, increased visceral fat mass, dyslipidemia, decreased arterial compliance, and diminished health-related quality of life. The Staying Strong And Healthy protocol is a telephone-delivered intervention led by a nurse coordinator to minimize the increased cardiovascular and metabolic risks associated with ADT. This study will evaluate the feasibility of the protocol and provides the foundation for future behavioral interventions across diverse populations of men on ADT.

Keywords: cancer; exercise; lifestyle change; nutrition; quality of life.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

References

    1. Alibhai SM, Breunis H, Timilshina N, Naglie G, Tannock I, Krahn M, … Tomlinson G(2015). Long-term impact of androgen-deprivation therapy on physical function and quality of life.Cancer, 121(14),2350–2357. 10.1002/cncr.29355 - DOI - PubMed
    1. American Cancer Society. (2018). Key statistics for prostate cancer. Retrieved from https://www.cancer.org/cancer/prostate-cancer/about/key-statistics.html
    1. American College of Sports Medicine, Thompson WR, Gordon NF, & Pescatello LS (2010).ACSM’s guidelines for exercise testing and prescription.8th ed. Philadelphia: Lippincott Williams & Wilkins.
    1. Baguley BJ, Bolam KA, Wright O, & Skinner TL (2017). The effect of nutrition therapy and exercise on cancer-related fatigue and quality of life in men with prostate cancer: A systematic review.Nutrients,9(9), 1003 https://doi.org10.3390/nu9091003 - PMC - PubMed
    1. Bandura A (2004). Health promotion by social cognitive means. Health education & behavior: the official publication of the society for public health education, 31(2), 143–164. 10.1177/1090198104263660 - DOI - PubMed

Publication types

MeSH terms

Substances