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Comment
. 2019 Aug 6;30(2):229-230.
doi: 10.1016/j.cmet.2019.07.007.

Acyl-CoA-Binding Protein Fuels Gliomagenesis

Junfeng Bi  1 , Paul S Mischel  2
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Acyl-CoA-Binding Protein Fuels Gliomagenesis

Junfeng Bi et al. Cell Metab. .
Free article

Abstract

Altered lipid metabolism is common in glioblastoma, but its role in tumorigenesis is not well understood. In this issue of Cell Metabolism, Duman et al. (2019) provide new insight into this process, demonstrating that acyl-CoA-binding protein (ACBP) drives glioblastoma growth by promoting mitochondrial long fatty acyl-CoA accumulation and β-oxidation.

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