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Review
. 2019 Jul 28;25(28):3722-3737.
doi: 10.3748/wjg.v25.i28.3722.

Surgical techniques and postoperative management to prevent postoperative pancreatic fistula after pancreatic surgery

Hiromichi Kawaida  1 , Hiroshi Kono  2 , Naohiro Hosomura  2 , Hidetake Amemiya  2 , Jun Itakura  2 , Hideki Fujii  3 , Daisuke Ichikawa  2
Affiliations
Review

Surgical techniques and postoperative management to prevent postoperative pancreatic fistula after pancreatic surgery

Hiromichi Kawaida et al. World J Gastroenterol. .

Abstract

Postoperative pancreatic fistula (POPF) is one of the most severe complications after pancreatic surgeries. POPF develops as a consequence of pancreatic juice leakage from a surgically exfoliated surface and/or anastomotic stump, which sometimes cause intraperitoneal abscesses and subsequent lethal hemorrhage. In recent years, various surgical and perioperative attempts have been examined to reduce the incidence of POPF. We reviewed several well-designed studies addressing POPF-related factors, such as reconstruction methods, anastomotic techniques, stent usage, prophylactic intra-abdominal drainage, and somatostatin analogs, after pancreaticoduodenectomy and distal pancreatectomy, and we assessed the current status of POPF. In addition, we also discussed the current status of POPF in minimally invasive surgeries, laparoscopic surgeries, and robotic surgeries.

Keywords: Distal pancreatectomy; Pancreaticoduodenectomy; Pancreatogastrostomy; Pancreatojejunostomy; Postoperative pancreatic fistula; Prophylactic drainage; Somatostatin analogs.

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Conflict of interest statement

Conflict-of-interest statement: No potential conflict of interest. No financial support.

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