Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Jul;8(Suppl 3):S263-S264.
doi: 10.21037/tau.2019.03.13.

Can the interplay between androgen signaling and PSMA expression be leveraged for theranostic applications?

Jaspreet S Batra  1 , Kenneth J Pienta  2 , Martin G Pomper  1   2 , Michael A Gorin  1   2 , Steven P Rowe  1   2
Affiliations
Editorial

Can the interplay between androgen signaling and PSMA expression be leveraged for theranostic applications?

Jaspreet S Batra et al. Transl Androl Urol. 2019 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: MG Pomper is a co-inventor on a U.S. patent covering 18F-DCFPyL and as such is entitled to a portion of any licensing fees and royalties generated by this technology. This arrangement has been reviewed and approved by the Johns Hopkins University in accordance with its conflict-of-interest policies. SP Rowe is a consultant to Progenics Pharmaceuticals, the licensee of 18F-DCFPyL. MA Gorin has served as a consultant to Progenics Pharmaceuticals. SP Rowe, MA Gorin, KJ Pienta, and MG Pomper receive research funding from Progenics Pharmaceuticals. The other author has no conflicts of interest to declare.

Comment on

References

    1. Dong L, Zieren RC, Xue W, et al. Metastatic prostate cancer remains incurable, why? Asian J Urol 2019;6:26-41. 10.1016/j.ajur.2018.11.005 - DOI - PMC - PubMed
    1. Bostwick DG, Pacelli A, Blute M, et al. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: a study of 184 cases. Cancer 1998;82:2256-61. 10.1002/(SICI)1097-0142(19980601)82:11<2256::AID-CNCR22>3.0.CO;2-S - DOI - PubMed
    1. Kulkarni HR, Singh A, Langbein T, et al. Theranostics of prostate cancer: from molecular imaging to precision molecular radiotherapy targeting the prostate specific membrane antigen. Br J Radiol 2018;91:20180308. 10.1259/bjr.20180308 - DOI - PMC - PubMed
    1. Evans MJ, Smith-Jones PM, Wongvipat J, et al. Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen. Proc Natl Acad Sci U S A 2011;108:9578-82. 10.1073/pnas.1106383108 - DOI - PMC - PubMed
    1. Hope TA, Truillet C, Ehman EC, et al. 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience. J Nucl Med 2017;58:81-4. 10.2967/jnumed.116.181800 - DOI - PMC - PubMed