How to guide the selection of patients for trimodality therapy: the case for tumor immune and stromal signature

Luca Boeri^{1

2}, R Jeffrey Karnes², Emanuele Montanari¹

Affiliations

¹ Department of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
² Department of Urology, Mayo Clinic, Rochester, MN, USA.

Editorial

Luca Boeri et al. Transl Androl Urol. 2019 Jul.

. 2019 Jul;8(Suppl 3):S329-S331.

doi: 10.21037/tau.2019.05.10.

Luca Boeri^{1

2}, R Jeffrey Karnes², Emanuele Montanari¹

¹ Department of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
² Department of Urology, Mayo Clinic, Rochester, MN, USA.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Impact of Immune and Stromal Infiltration on Outcomes Following Bladder-Sparing Trimodality Therapy for Muscle-Invasive Bladder Cancer.
Efstathiou JA, Mouw KW, Gibb EA, Liu Y, Wu CL, Drumm MR, da Costa JB, du Plessis M, Wang NQ, Davicioni E, Feng FY, Seiler R, Black PC, Shipley WU, Miyamoto DT. Efstathiou JA, et al. Eur Urol. 2019 Jul;76(1):59-68. doi: 10.1016/j.eururo.2019.01.011. Epub 2019 Feb 1. Eur Urol. 2019. PMID: 30712971 Free PMC article.

1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin 2018;68:7-30. 10.3322/caac.21442 - DOI - PubMed
1. García-Perdomo HA, Montes-Cardona CE, Guacheta M, et al. Muscle-invasive bladder cancer organ-preserving therapy: systematic review and meta-analysis. World J Urol. 2018;36:1997-2008. 10.1007/s00345-018-2384-6 - DOI - PubMed
1. Giacalone NJ, Shipley WU, Clayman RH, et al. Long-term Outcomes After Bladder-preserving Tri-modality Therapy for Patients with Muscle-invasive Bladder Cancer: An Updated Analysis of the Massachusetts General Hospital Experience. Eur Urol 2017;71:952-60. 10.1016/j.eururo.2016.12.020 - DOI - PubMed
1. National Institute for Health and Care Excellence. Bladder cancer: diagnosis and management. NICE. 2015. Available online: https://www.nice.org.uk/guidance/ng2/chapter/1-Recommendations - PubMed
1. Flaig TW, Spiess PE, Agarwal N, et al. NCCN guidelines insights: bladder cancer, version 5.2018. J Natl Compr Canc Netw 2018;16:1041-3. 10.6004/jnccn.2018.0072 - DOI - PubMed