EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella^{1

2}, Anca M Avram³, Ioannis Iakovou⁴, Jennifer Kwak⁵, Susan A Lawson³, Elizabeth Lulaj⁶, Markus Luster⁷, Arnoldo Piccardo⁸, Matthias Schmidt⁹, Mark Tulchinsky¹⁰, Frederick A Verburg⁷, Ely Wolin¹¹

Affiliations

¹ Clinic for Nuclear Medicine and Thyroid Competence Center, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Via Ospedale 6, CH-6500, Bellinzona, Switzerland. Luca.Giovanella@eoc.ch.
² Clinic for Nuclear Medicine, University Hospital and University of Zurich, Zurich, Switzerland. Luca.Giovanella@eoc.ch.
³ Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, MI, USA.
⁴ Department of Nuclear Medicine, Papageorgiou Hospital, Aristotle University, Thessaloniki, Greece.
⁵ Division of Nuclear Medicine, Department of Radiology, University of Colorado, Denver, CO, USA.
⁶ Division of Nuclear Medicine, Department of Radiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
⁷ Clinic for Nuclear Medicine, Marburg University Hospital, Marburg, Germany.
⁸ Nuclear Medicine Unit, Imaging Department, Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
⁹ Clinic for Nuclear Medicine, Cologne University Hospital, Cologne, Germany.
¹⁰ Division of Nuclear Medicine, Department of Radiology, Penn State University, Hershey, PA, USA.
¹¹ Division of Nuclear Medicine, Department of Radiology, David Grant Medical Center, Vacaville, CA, USA.

PMID: 31392371
DOI: 10.1007/s00259-019-04472-8

EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella et al. Eur J Nucl Med Mol Imaging. 2019 Nov.

. 2019 Nov;46(12):2514-2525.

doi: 10.1007/s00259-019-04472-8. Epub 2019 Aug 7.

Authors

Affiliations

¹ Clinic for Nuclear Medicine and Thyroid Competence Center, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Via Ospedale 6, CH-6500, Bellinzona, Switzerland. Luca.Giovanella@eoc.ch.
² Clinic for Nuclear Medicine, University Hospital and University of Zurich, Zurich, Switzerland. Luca.Giovanella@eoc.ch.
³ Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, MI, USA.
⁴ Department of Nuclear Medicine, Papageorgiou Hospital, Aristotle University, Thessaloniki, Greece.
⁵ Division of Nuclear Medicine, Department of Radiology, University of Colorado, Denver, CO, USA.
⁶ Division of Nuclear Medicine, Department of Radiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
⁷ Clinic for Nuclear Medicine, Marburg University Hospital, Marburg, Germany.
⁸ Nuclear Medicine Unit, Imaging Department, Ente Ospedaliero Ospedali Galliera, Genoa, Italy.
⁹ Clinic for Nuclear Medicine, Cologne University Hospital, Cologne, Germany.
¹⁰ Division of Nuclear Medicine, Department of Radiology, Penn State University, Hershey, PA, USA.
¹¹ Division of Nuclear Medicine, Department of Radiology, David Grant Medical Center, Vacaville, CA, USA.

PMID: 31392371
DOI: 10.1007/s00259-019-04472-8

Abstract

Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the ^99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively.

Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature.

Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

Keywords: 99mTc-sestaMIBI, 18F-fluorodeoxyglucose; Radioiodine uptake test; Scintigraphy; Thyroid.

PubMed Disclaimer

References

1. Minerva Endocrinol. 2002 Mar;27(1):53-7 - PubMed
1. Nuklearmedizin. 2013;52(4):130-6 - PubMed
1. Eur J Nucl Med Mol Imaging. 2014 Aug;41(8):1636 - PubMed
1. N Engl J Med. 2012 Aug 23;367(8):705-15 - PubMed
1. Ann Surg Oncol. 2007 Nov;14(11):3210-5 - PubMed

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
- Springer
Medical
- ClinicalTrials.gov
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Affiliations

EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Authors

Affiliations

Abstract

References

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical