Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec;69(6):678-681.
doi: 10.1097/MPG.0000000000002464.

Continuous Feedings Are Not Associated With Lower Rates of Gastroesophageal Reflux When Compared With Bolus Feedings

Affiliations

Continuous Feedings Are Not Associated With Lower Rates of Gastroesophageal Reflux When Compared With Bolus Feedings

Lisa B Mahoney et al. J Pediatr Gastroenterol Nutr. 2019 Dec.

Abstract

Gastroesophageal reflux disease is common in children with gastrostomy tubes. Clinicians often transition to continuous feedings in an attempt to reduce reflux burden, though there is limited data to support this practice. In this retrospective study, we analyzed 24-hour multichannel intraluminal impedance with pH studies in 18 children with gastrostomy tubes receiving exclusive enteral nutrition with a combination of daytime bolus and overnight continuous feedings. There were no significant differences in the rate of reflux (reflux events per hour) between no feeding, bolus feeding, and continuous feeding periods overall or stratified by prior fundoplications (P > 0.40). After adjusting for age, BMI, feeding rate, and feeding volume in multivariate analysis, there were no significant differences in the risk of reflux between different feeding periods. These results suggest that continuous feedings may not offer a significant advantage in reducing reflux burden.

PubMed Disclaimer

Conflict of interest statement

Potential conflict of interest: None declared

References

    1. Ojo O, Keaveney E, Wang X-H, et al. The Effect of Enteral Tube Feeding on Patients’ Health-Related Quality of Life: A Systematic Review. Nutrients. 2019;11(5). - PMC - PubMed
    1. Singhal S, Baker SS, Bojczuk GA, et al. Tube Feeding in Children. Pediatr Rev. 2017;38(1):23–34. - PubMed
    1. Ichimaru S Methods of Enteral Nutrition Administration in Critically Ill Patients: Continuous, Cyclic, Intermittent, and Bolus Feeding. Nutr Clin Pract. 2018;33(6):790–5. - PubMed
    1. Coben RM, Weintraub A, DiMarino AJ, et al. Gastroesophageal reflux during gastrostomy feeding. Gastroenterology. 1994;106(1):13–8. - PubMed
    1. Aumar M, Lalanne A, Guimber D, et al. Influence of Percutaneous Endoscopic Gastrostomy on Gastroesophageal Reflux Disease in Children. J Pediatr 2018;197:116–20. - PubMed

Publication types