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Case Reports
. 2019 Aug;98(32):e16760.
doi: 10.1097/MD.0000000000016760.

Adenoid cystic carcinoma of the breast in a male: A case report

Wenyang Pang  1 , Zhengyi Wang, Xiaoyan Jin, Qiang Zhang
Affiliations
Case Reports

Adenoid cystic carcinoma of the breast in a male: A case report

Wenyang Pang et al. Medicine (Baltimore). 2019 Aug.

Abstract

Rationale: Adenoid cystic carcinoma (ACC) of the breast is an infrequent neoplasm, and the occurrence in males is rare. Therefore, diagnostic and therapeutic challenges are inevitable.

Patient concerns: Herein, we present a case of a 44-year-old man with a tumor on his right breast that he had known about for 6 years.

Diagnoses: The patient underwent a lumpectomy, and the histological examination confirmed a diagnosis of ACC.

Interventions: Modified radical mastectomy was subsequently conducted in the patient. No positive lymph nodes were observed in the postoperative pathological examination. Following the surgery, the patient received adjuvant chemotherapy.

Outcomes: The patient remained recurrence-free at 26 months.

Lessons: Compared to female breast ACC, male breast ACC may behave differently biologically and have a different prognosis. Our case will provide more diagnostic and treatment experience to deal with this disease.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Ultrasonography of the tumor demonstrating an ill-defined hypoechoic lesion in the subareolar region with minimal vascularity observed on color Doppler interrogation (arrow).
Figure 2
Figure 2
(A) Sagittal, TSE, T1-weighted MRI illustrating that the tumor was hypointense in T1 signal (arrow). (B) Fat-saturated, sagittal, T2-weighted MRI showing that the tumor was hyperintense in T2 signal (arrow). (C) Early-phase sagittal, dynamic, eTHRIVE, contrast-enhanced MRI showing a rapidly and homogeneously enhancing tumor (arrow). MRI = magnetic resonance imaging.
Figure 3
Figure 3
Characteristics of H&E photomicrographs of male breast adenoid cystic carcinoma. (A) Solid and cribriform patterns. (B) Tubular pattern with perineural invasion.
See this image and copyright information in PMC

References

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