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. 1988 Nov;56(11):3004-6.
doi: 10.1128/iai.56.11.3004-3006.1988.

Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice

D M Williams  1 , G I Byrne, B Grubbs, T J Marshal, J Schachter
Affiliations

Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice

D M Williams et al. Infect Immun. 1988 Nov.

Abstract

In a model of pneumonia caused by murine Chlamydia trachomatis, depletion experiments with monoclonal antibody to gamma interferon (IFN-gamma) made mice more susceptible. Repletion experiments giving exogenous recombinant murine IFN-gamma were not consistently protective. IFN-gamma may be necessary but not sufficient in host defense against the organism.

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References

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