Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Aug 9;20(16):3879.
doi: 10.3390/ijms20163879.

Inflammation and Cardiovascular Diseases: The Most Recent Findings

Affiliations
Editorial

Inflammation and Cardiovascular Diseases: The Most Recent Findings

Daniela Sorriento et al. Int J Mol Sci. .

Abstract

The series of reactive biological events that we identify as inflammation has been investigated in recent years and unveiled as an important mechanism for regeneration. The study of the underlying complexity has been boosted by new technological innovation in research and allowed the identification of inflammatory responses as the basis of diseases that were considered degenerative rather than regenerative in nature. This is the case for cardiovascular diseases, from the organ damage that follows an acute event to the damage of target organs exposed to chronic risk factors. This editorial explores innovative aspects of inflammation in the setup of cardiovascular risk factors and diseases.

Keywords: NFκB; cardiovascular risk; cytokines; heart failure; inflammation; inflammatory diseases.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Ridker P.M., Everett B.M., Thuren T., MacFadyen J.G., Chang W.H., Ballantyne C., Fonseca F., Nicolau J., Koenig W., Anker S.D., et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N. Engl. J. Med. 2017;377:1119–1131. doi: 10.1056/NEJMoa1707914. - DOI - PubMed
    1. Fiordelisi A., Iaccarino G., Morisco C., Coscioni E., Sorriento D. NFkappaB is a Key Player in the Crosstalk between Inflammation and Cardiovascular Diseases. Int. J. Mol. Sci. 2019;20:1599. doi: 10.3390/ijms20071599. - DOI - PMC - PubMed
    1. Liccardo D., Cannavo A., Spagnuolo G., Ferrara N., Cittadini A., Rengo C., Rengo G. Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease. Int. J. Mol. Sci. 2019;20:1414. doi: 10.3390/ijms20061414. - DOI - PMC - PubMed
    1. Mercurio V., Lobasso A., Barbieri L., Parrella P., Ciervo D., Liccardo B., Bonaduce D., Tocchetti C.G., De Paulis A., Rossi F.W. Inflammatory, Serological and Vascular Determinants of Cardiovascular Disease in Systemic Lupus Erythematosus Patients. Int. J. Mol. Sci. 2019;20:2154. doi: 10.3390/ijms20092154. - DOI - PMC - PubMed
    1. Varricchi G., Loffredo S., Borriello F., Pecoraro A., Rivellese F., Genovese A., Spadaro G., Marone G. Superantigenic Activation of Human Cardiac Mast Cells. Int. J. Mol. Sci. 2019;20:1828. doi: 10.3390/ijms20081828. - DOI - PMC - PubMed

Publication types

LinkOut - more resources