A Light Touch on Sociability
- PMID: 31398332
- DOI: 10.1016/j.cell.2019.07.022
A Light Touch on Sociability
Abstract
Autism spectrum disorder (ASD) is prevalent, complex, and heterogeneous, and currently there is no cure. Identifying shared mechanisms across the ASD spectrum is of utmost importance for therapeutic intervention. Orefice et al. show that tackling the GABAA receptor pathway in the peripheral somatosensory system in various ASD mouse models rescues core ASD-like phenotypes.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.Cell. 2019 Aug 8;178(4):867-886.e24. doi: 10.1016/j.cell.2019.07.024. Cell. 2019. PMID: 31398341 Free PMC article.
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