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Comment
. 2019 Sep;29(9):694-695.
doi: 10.1038/s41422-019-0211-2.

Histone lysine de-β-hydroxybutyrylation by SIRT3

Susan M Abmayr  1   2 , Jerry L Workman  3
Affiliations
Comment

Histone lysine de-β-hydroxybutyrylation by SIRT3

Susan M Abmayr et al. Cell Res. 2019 Sep.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
SIRT3 is only able to bind and remove bhb from lysine 16 of histone H4. Removal of bhb from lysines 4, 8 and 12 is blocked by flanking glycine residues. The rotational freedom of these glycines is detrimental to interaction of SIRT3 with the backbone of these modified lysines
See this image and copyright information in PMC

Comment on

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