Association of Sleep Duration and Insomnia Symptoms with Components of Metabolic Syndrome and Inflammation in Middle-Aged and Older Adults with Metabolic Syndrome in Taiwan
- PMID: 31404954
- PMCID: PMC6723777
- DOI: 10.3390/nu11081848
Association of Sleep Duration and Insomnia Symptoms with Components of Metabolic Syndrome and Inflammation in Middle-Aged and Older Adults with Metabolic Syndrome in Taiwan
Abstract
The study determined the association of sleep duration and insomnia symptoms with the components of metabolic syndrome and inflammation in middle-aged and older adults with metabolic syndrome in Taiwan. This cross-sectional study used the database compiled in Taiwan between 2004-2013. A total of 26,016 volunteers aged 35 years and above were selected. Metabolic syndrome was defined according to the International Diabetes Federation. Compared with regular sleep duration (6-8 h/day), short (<6 h/day) or long sleep duration (>8 h/day) and insomnia symptoms significantly increased the odds ratios of high waist circumference, high blood pressure, low high-density lipoprotein-cholesterol, high triglycerides, high fasting blood glucose, and high C-reactive protein. Insomnia symptoms did not modify the effects of sleep duration on the components of metabolic syndrome and inflammation. Our study suggests that short or long sleep duration and insomnia symptoms may have an adverse effect on metabolic syndrome and inflammation.
Keywords: cross-sectional study; inflammation; insomnia symptoms; metabolic syndrome; sleep duration; sleep quality.
Conflict of interest statement
The authors declare no conflict of interest.
Similar articles
-
The Link of Self-Reported Insomnia Symptoms and Sleep Duration with Metabolic Syndrome: A Chinese Population-Based Study.Sleep. 2016 Jun 1;39(6):1261-6. doi: 10.5665/sleep.5848. Sleep. 2016. PMID: 27070137 Free PMC article.
-
Short Sleep Duration Increases Metabolic Impact in Healthy Adults: A Population-Based Cohort Study.Sleep. 2017 Oct 1;40(10). doi: 10.1093/sleep/zsx130. Sleep. 2017. PMID: 28977563
-
Association of Sleep Duration and Self-Reported Insomnia Symptoms with Metabolic Syndrome Components among Middle-Aged and Older Adults.Int J Environ Res Public Health. 2022 Sep 15;19(18):11637. doi: 10.3390/ijerph191811637. Int J Environ Res Public Health. 2022. PMID: 36141918 Free PMC article.
-
The association between insomnia and the risk of metabolic syndrome: A systematic review and meta-analysis.J Clin Neurosci. 2021 Jul;89:430-436. doi: 10.1016/j.jocn.2021.05.039. Epub 2021 May 29. J Clin Neurosci. 2021. PMID: 34074598
-
Menopause research in Latin America.Climacteric. 2019 Feb;22(1):17-21. doi: 10.1080/13697137.2018.1540565. Epub 2018 Dec 21. Climacteric. 2019. PMID: 30572731 Review.
Cited by
-
Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype.Alzheimers Dement. 2022 Mar;18(3):408-421. doi: 10.1002/alz.12405. Epub 2021 Jul 26. Alzheimers Dement. 2022. PMID: 34310026 Free PMC article.
-
Protective effects and molecular mechanisms of tea polyphenols on cardiovascular diseases.Front Nutr. 2023 Jun 28;10:1202378. doi: 10.3389/fnut.2023.1202378. eCollection 2023. Front Nutr. 2023. PMID: 37448666 Free PMC article. Review.
-
Association of Insomnia, Lipid Profile, and Lipid-Lowering Medications: A Narrative Review.Rev Cardiovasc Med. 2025 Jan 15;26(1):24978. doi: 10.31083/RCM24978. eCollection 2025 Jan. Rev Cardiovasc Med. 2025. PMID: 39867194 Free PMC article. Review.
-
Sleep duration predicts subsequent long-term mortality in patients with type 2 diabetes: a large single-center cohort study.Cardiovasc Diabetol. 2022 Apr 27;21(1):60. doi: 10.1186/s12933-022-01500-0. Cardiovasc Diabetol. 2022. PMID: 35477572 Free PMC article.
-
Association of Two Indices of Insulin Resistance Marker with Abnormal Liver Function Tests: A Cross-Sectional Population Study in Taiwanese Adults.Medicina (Kaunas). 2021 Dec 21;58(1):4. doi: 10.3390/medicina58010004. Medicina (Kaunas). 2021. PMID: 35056312 Free PMC article.
References
-
- Gami A.S., Witt B.J., Howard D.E., Erwin P.J., Gami L.A., Somers V.K., Montori V.M. Metabolic syndrome and risk of incident cardiovascular events and death: A systematic review and meta-analysis of longitudinal studies. J. Am. Coll. Cardiol. 2007;49:403–414. doi: 10.1016/j.jacc.2006.09.032. - DOI - PubMed
-
- Gundogan K., Bayram F., Capak M., Tanriverdi F., Karaman A., Ozturk A., Altunbas H., Gokce C., Kalkan A., Yazici C. Prevalence of metabolic syndrome in the Mediterranean region of Turkey: Evaluation of hypertension, diabetes mellitus, obesity and dyslipidemia. Metab. Syndr. Relat. Disord. 2009;7:427–434. doi: 10.1089/met.2008.0068. - DOI - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases
Research Materials