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. 2019 Apr-Jun;12(2):97-112.
doi: 10.25122/jml-2019-0026.

Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury

Simona Isabelle Stoica  1   2 , Ioana Tănase  1   2 , Vlad Ciobanu  3 , Gelu Onose  1   2
Affiliations

Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury

Simona Isabelle Stoica et al. J Med Life. 2019 Apr-Jun.

Abstract

We found differences related to the neuro-functional deficiency and clinical progress, among non-consumers and chronic consumers of ethanol, with recent traumatic spinal cord injury (SCI). We present a synthesis of related data on lesion mechanisms in post-traumatic myelogenous disorders, namely some of the alcohols and their actions on the nervous system, with details on the influences exerted, in such afflictions, by the chronic consumption of ethanol. The subject is not frequently approached - according to a literature review with systematic elements, which we have done before - thus constituting a niche that deserves to be further explored. The applicative component of the article highlights statistical data resulted from a retrospective study regarding the specialized casuistry from the Neuromuscular Recovery Clinic of the "Bagdasar Arseni" Emergency Clinical Hospital, following the comparative analysis of two groups of patients with recent SCI: non-consumers - the control group (n=780) - and chronic ethanol consumers - the study group (n=225) - with the addition of a prospective pilot component. Data processing has been achieved with SPSS 24. The American Spinal Injury Association Impairment Scale (AIS) mean motor scores differ significantly (tests: Mann-Whitney and t) between the control and study group in favor of the second, both at admission (p<0.001) and at discharge (p<0.001). AIS mean sensitive scores differ between the two lots, and also in favor of the study, but statistically significant only at discharge (p=0.048); the difference at admission is not significant (p=0.51) - possibly because of alcoholic-nutritional polyneuropathy. These findings, with numerous related details, later presented in the text, are surprising, which requires further studies and attempts of understanding.

Keywords: chronic alcoholism; ethanol; literature review; polyethylene glycol; recent traumatic spinal cord injury.

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Figures

Figure 1:
Figure 1:
Histogram of patient ages for the lot.
Figure 2:
Figure 2:
Distribution of patient ages by sex.
Figure 3:
Figure 3:
Distribution of patients by gender and alcohol consumption.
Figure 4:
Figure 4:
Distribution of patients (chronic ethanolic and non-ethanolic) for the pathophysiological mechanism of traumatic lesion in SCI.
Figure 5:
Figure 5:
Distribution of AIS motor scores for the chronic ethanolic and non-ethanolic patients.
Figure 6:
Figure 6:
Percentage distribution of SMAST results for patient admitted to the Neuro-muscular Recovery Clinic, at 01.03.2019.
See this image and copyright information in PMC

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