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. 2020 Mar;105(3):e107-e110.
doi: 10.3324/haematol.2019.220863. Epub 2019 Aug 14.

Genomic and outcome analysis of adult T-cell lymphoblastic lymphoma

Zhaoming Li  1   2 , Yue Song  1   2 , Yanjie Zhang  1   3 , Chaoping Li  1   3 , Yingjun Wang  1   3 , Weili Xue  1   3 , Lisha Lu  1   3 , Mengyuan Jin  1   3 , Zhiyuan Zhou  1   3 , Xinhua Wang  1   2 , Ling Li  1   2 , Lei Zhang  1   2 , Xin Li  1   2 , Xiaorui Fu  1   2 , Zhenchang Sun  1   2 , Jingjing Wu  1   2 , Xudong Zhang  1   2 , Hui Yu  1   2 , Feifei Nan  1   2 , Yu Chang  1   2 , Jiaqin Yan  1   2 , Xiaoyan Feng  1   2 , Xiaolong Wu  1   2 , Guannan Wang  4 , Dandan Zhang  4 , Wencai Li  4 , Feixiang Li  5 , Yuan Zhang  6 , Ken H Young  7 , Mingzhi Zhang  8   2
Affiliations

Genomic and outcome analysis of adult T-cell lymphoblastic lymphoma

Zhaoming Li et al. Haematologica. 2020 Mar.
No abstract available

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Figures

Figure 1
Figure 1
Mutational landscape of adult T-cell lymphoblastic lymphoma. The heat map shows the somatic mutational profile of the adult T-cell lymphoblastic lymphoma (T-LBL) cohort separated by gene functional groups. Rows represent individual genes, and columns represent individual tumors. Blocks are color-coded by the functional type of mutation. The top panel shows the clinical characteristics of the T-LBL patient cohort.
Figure 2
Figure 2
Mutational status and outcome analysis in adult T-cell lymphoblastic lymphoma patients who have been treated uniformly according to the hyper-CVAD regimen (n=66). (A) PFS and OS in adult T-cell lymphoblastic lymphoma (T-LBL) patients according to N/F mutational status. (B) PFS and OS in adult T-LBL patients according to PHF6 mutational status. (C) PFS and OS in adult T-LBL patients according to the combined genotype of N/F and PHF6. Survival curves were estimated using the Kaplan–Meier method and compared using a two-sided log-rank test. PFS: progression-free survival; OS: overall survival.
See this image and copyright information in PMC

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