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Review
. 2019 Jul 30:7:312.
doi: 10.3389/fped.2019.00312. eCollection 2019.

Principlism and Personalism. Comparing Two Ethical Models Applied Clinically in Neonates Undergoing Extracorporeal Membrane Oxygenation Support

Affiliations
Review

Principlism and Personalism. Comparing Two Ethical Models Applied Clinically in Neonates Undergoing Extracorporeal Membrane Oxygenation Support

Matteo Di Nardo et al. Front Pediatr. .

Abstract

Extracorporeal membrane oxygenation (ECMO) is a technology used to temporarily assist critically ill patients with acute and reversible life-threatening cardiac and/or respiratory failure. This technology can often be lifesaving but is also associated with several complications that may contribute to reduced survival. Currently, neonates supported with ECMO are complex and bear an increased risk of mortality. This means that clinicians must be particularly prepared not only to deal with complex clinical scenarios, but also ethical issues associated with ECMO. In particular, clinicians should be trained to handle unsuccessful ECMO runs with attention to high quality end of life care. Within this manuscript we will compare and contrast the application of two ethical frameworks, used in the authors' institutions (Toronto and Rome). This is intended to enhance a broader understanding of cultural differences in applied ethics which is useful to the clinician in an increasingly multicultural and diverse patient mix.

Keywords: ECMO—extracorporeal membrane oxygenation; bioethic; neonates; personalism; principlism and code of ethics.

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Figures

Figure 1
Figure 1
Principlist biomedical ethics.
Figure 2
Figure 2
Facilitating ethical and medical practice—the 4 box method.
Figure 3
Figure 3
Personalist biomedical ethics.
Figure 4
Figure 4
(A) Principlist Bioethics method applied at bedside while a neonate is undergoing ECMO. (B) Personalist Bioethics method applied at bedside while a neonate is undergoing ECMO.

References

    1. Kirsch R, Clark J. The ethics of ECLS. In: Brogan TV, Lequier L, Lorusso R, MacLaren G, Peek G, et al. (eds.). Extracorporeal Life Support: The ELSO Red Book, 5th ed Ann Arbor: ELSO; (2017). p. 781–94.
    1. Bein T, Brodie D. Understanding ethical decisions for patients on extracorporeal life support. Intensive Care Med. (2017) 43:1510–11. 10.1007/s00134-017-4781-5 - DOI - PMC - PubMed
    1. International Summary of ELSO Registry Report. Extracorporeal Life Support Organization (ELSO), Ann Arbor, MI: (2018) Available online at: https://www.elso.org/Registry/Statistics/InternationalSummary.aspx
    1. Kirsch R, Munson D. Ethical and end of life considerations for neonates requiring ECMO support. Semin Perinatol. (2018) 42:129–37. 10.1053/j.semperi.2017.12.009 - DOI - PubMed
    1. Kirsch RE, Balit CR, Carnevale FA, Latour JM, Larcher V. Ethical, cultural, social, and individual considerations prior to transition to limitation or withdrawal of life-sustaining therapies. Pediatr Crit Care Med. (2018) 19(Suppl. 2):S10–18. 10.1097/PCC.0000000000001488 - DOI - PubMed

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