Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): An international, multicentre, randomised, controlled equivalence trial
- PMID: 31418482
- DOI: 10.1111/apa.14943
Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): An international, multicentre, randomised, controlled equivalence trial
Comment on
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Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial.Lancet. 2019 Feb 16;393(10172):664-677. doi: 10.1016/S0140-6736(18)32485-1. Epub 2019 Feb 14. Lancet. 2019. PMID: 30782342 Free PMC article. Clinical Trial.
References
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- Coleman K, Robertson ND, Dissen GA, et al. Isoflurane anesthesia has long-term consequences on motor and behavioral development in infant Rhesus Macaques. Anesthesiology. 2017;126:74-84.
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- Lunardi N, Sica R, Atluri N, et al. Disruption of rapid eye movement sleep homeostasis in adolescent rats after neonatal anesthesia. Anesthesiology. 2019;130:981-994.
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- US Food and Drug Administration. Drug safety communication: FDA approves label changes for use of general anesthetic and sedation drugs in young children; 2017.
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- Warner DO, Chelonis JJ, Paule MG, et al. Performance on the operant test battery in young children exposed to procedures requiring general anaesthesia: the MASK study. Br J Anaesth. 2019;122:470-479.
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