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. 2019 Oct;179(10):1987-2033.
doi: 10.1002/ajmg.a.61310. Epub 2019 Aug 16.

Recognition and management of adults with Turner syndrome: From the transition of adolescence through the senior years

Angela E Lin  1 , Siddharth K Prakash  2 , Niels H Andersen  3 , Mette H Viuff  4 , Lynne L Levitsky  5 , Michelle Rivera-Davila  6 , Melissa L Crenshaw  7 , Lars Hansen  8 , Mary K Colvin  9   10 , Frances J Hayes  11 , Evelyn Lilly  12 , Emma A Snyder  1 , Shahla Nader-Eftekhari  13 , Melissa B Aldrich  14 , Ami B Bhatt  15   16 , Laura M Prager  10 , Ana Arenivas  17   18 , Anne Skakkebaek  19 , Marcie A Steeves  1 , Jeffrey B Kreher  20 , Claus H Gravholt  4
Affiliations

Recognition and management of adults with Turner syndrome: From the transition of adolescence through the senior years

Angela E Lin et al. Am J Med Genet A. 2019 Oct.

Abstract

Turner syndrome is recognized now as a syndrome familiar not only to pediatricians and pediatric specialists, medical geneticists, adult endocrinologists, and cardiologists, but also increasingly to primary care providers, internal medicine specialists, obstetricians, and reproductive medicine specialists. In addition, the care of women with Turner syndrome may involve social services, and various educational and neuropsychologic therapies. This article focuses on the recognition and management of Turner syndrome from adolescents in transition, through adulthood, and into another transition as older women. It can be viewed as an interpretation of recent international guidelines, complementary to those recommendations, and in some instances, an update. An attempt was made to provide an international perspective. Finally, the women and families who live with Turner syndrome and who inspired several sections, are themselves part of the broad readership that may benefit from this review.

Keywords: Turner syndrome; clinical history; hormone replacement therapy; infertility; sex chromosome abnormality syndrome; transitioning.

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References

REFERENCES

    1. Adler, R. H., Herschkowitz, N., & Minder, C. E. (2005). The abnormalities of carbohydrate metabolism in Turner syndrome: Analysis of risk factors associated with impaired glucose tolerance. European Journal of Pediatrics, 164, 442-447. https://doi.org/10.1007/s00431-005-1643-x
    1. Ahiko, N., Baba, Y., Tsuji, M., Horikawa, R., & Moriyama, K. (2019). Investigation of maxillofacial morphology and oral characteristics with Turner syndrome and early mixed dentition. Congenital Anomalies, 59, 11-17. https://doi.org/10.1111/cga.12284
    1. Alexiou, G. A., Varela, M., Dimitriadis, E., Patereli, A., Papadakis, V., Stefanaki, K., … Prodromou, N. (2014). Brain tumors in Turner syndrome. European Journal of Medical Genetics, 57, 312-313. https://doi.org/10.1016/j.ejmg.2014.04.001
    1. Al-Niaimi, F., & Cox, N. (2009). Cellulitis and lymphedema: A vicious cycle. Journal of Lymphoedema, 4, 38-42.
    1. American Academy of Pediatrics, American Academy of Family Physicians, American College of Physicians, & Transitions Clinical Report Authoring Group. (2011). Supporting the health care transition from adolescence to adulthood in the medical home. Pediatrics, 128, 182-200. https://doi.org/10.1542/peds.2011-0969

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