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Review
. 2019 Oct;21(10):1187-1196.
doi: 10.1002/ejhf.1585. Epub 2019 Aug 16.

Heart failure around the world

Jasper Tromp  1   2   3 , João Pedro Ferreira  4 , Satit Janwanishstaporn  5 , Monica Shah  6 , Barry Greenberg  7 , Faiez Zannad  4 , Carolyn S P Lam  1   2   3   8
Affiliations
Free article
Review

Heart failure around the world

Jasper Tromp et al. Eur J Heart Fail. 2019 Oct.
Free article

Abstract

With increasingly large sample sizes required to demonstrate event reduction, heart failure outcome trials are no longer being performed in a small group of selected patients and countries, but at a global scale with worldwide contribution of patients from countries with considerable differences in background therapy, socioeconomic status and healthcare practices. Recent studies have highlighted how socioeconomic determinants rather than geographical factors may underlie the heterogeneity of patient populations across the globe. Therefore, in this review, we evaluated (i) regional differences in patient characteristics and outcomes in recent epidemiologic studies; (ii) regional differences in worldwide representativeness of clinical trial populations; and (iii) the role of socioeconomic determinants in driving country differences in heart failure trial enrolment and clinical outcomes.

Keywords: Geographic differences; Heart failure; Outcome; Socioeconomic status.

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References

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