Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Sep;21(9):1393-1398.
doi: 10.1111/jch.13648. Epub 2019 Aug 17.

Diagnostic accuracy of an algorithm for detecting atrial fibrillation in a wrist-type pulse wave monitor

Tomoyuki Kabutoya  1 , Shinichi Takahashi  2 , Tomonori Watanabe  1 , Yasushi Imai  1 , Kazuhiro Uemoto  2 , Nobuhiko Yasui  2 , Kazuomi Kario  1
Affiliations

Diagnostic accuracy of an algorithm for detecting atrial fibrillation in a wrist-type pulse wave monitor

Tomoyuki Kabutoya et al. J Clin Hypertens (Greenwich). 2019 Sep.

Abstract

We evaluated the diagnostic value of atrial fibrillation (AF) measured by a wrist-type pulse wave monitor in this case-control study. Six serial pulse wave values (three in the left and three in the right wrist) were measured using a wrist-type monitor in 29 AF patients and 30 subjects with sinus rhythm. We defined "monitor AF in irregular pulse peak (IPP) 15/20/25" as follows: (a) IPP: |interval of pulse peak - the average of the interval of the pulse peak| ≥ the average of the interval of the pulse peak × 15/20/25%; (b) irregular heartbeat (IHB): beats of IPP ≥ total pulse × 20%; and (c) monitor AF: ≥4 IHBs of the six pulse wave measurements. In IPP 15, the sensitivity and specificity were 0.97 and 1.00, respectively. Pulse wave analysis by a wrist-type monitor was shown to have high sensitivity and specificity for the diagnosis of AF.

Keywords: atrial fibrillation; hypertension; pulse wave.

PubMed Disclaimer

Conflict of interest statement

K Kario received research grants from A&D Company Limited; N Yasui, S Takahashi, and K Uemoto are employees of A&D Company Limited; and all other authors report no potential conflict of interest in relation to this article.

This study was conducted as a joint research between Jichi Medical University School of Medicine and A&D Company, Limited.

Figures

Figure 1
Figure 1
The measurement of pulse wave. A, A wrist‐type pulse wave monitor (UW‐330BLE; A&D), B, photoplethysmography, C, real measurement of pulse wave and electrocardiogram, D, protocol of this study
Figure 2
Figure 2
The association between the interval of the pulse wave and heart rate. A, Patients with sinus rhythm, B, patients with atrial fibrillation
Figure 3
Figure 3
Bland‐Altman plot of the interval of the pulse wave and heart rate values. SD: standard deviation. A, Patients with sinus rhythm, B, patients with atrial fibrillation
Figure 4
Figure 4
The distribution of sinus rhythm and atrial fibrillation according to the number of IHBs of three measurements. A, IPP 15%, B, IPP 20%, C, IPP 25%. Black bars = patients with atrial fibrillation; gray bars = sinus rhythm patients. IHB, irregular heartbeat; IPP, irregular pulse peak
See this image and copyright information in PMC

References

    1. Majeed A, Moser K, Carroll K. Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994–1998: analysis of data from the general practice research database. Heart. 2001;86:284‐288. - PMC - PubMed
    1. Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285:2370‐2375. - PubMed
    1. Heeringa J, van der Kuip D, Hofman A, et al. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006;27:949‐953. - PubMed
    1. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22:983‐988. - PubMed
    1. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation. 1998;98:946‐952. - PubMed

Publication types