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Review
. 2019 Nov 15:182:111612.
doi: 10.1016/j.ejmech.2019.111612. Epub 2019 Aug 10.

Application of glycosylation in targeted drug delivery

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Review

Application of glycosylation in targeted drug delivery

Fang Chen et al. Eur J Med Chem. .

Abstract

Sugar, as a carrier of human energy and an important bioinformatics molecule, plays a vital role in many important physiological processes, and can control the transmission of bioinformatics by specific recognition with biological molecules such as proteins. Herein, the mechanism of glycosylation-targeted drug delivery was described, various glycosylation methods were summarized, and the applications of glycosylation-targeted drug delivery in liver targeting, brain targeting and lung targeting were discussed. At the same time, the problems of glycosylation targeted drug delivery were suggested, and the application prospects of glycosylation targeting drug delivery were expected.

Keywords: Application; Glycosylation; Mechanisms; Targeted drug delivery.

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