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Review
. 2019 Oct;119(10):1563-1572.
doi: 10.1055/s-0039-1693702. Epub 2019 Aug 17.

MicroRNAs as Regulators and Biomarkers of Platelet Function and Activity in Coronary Artery Disease

Stefan Stojkovic  1 , Anne Yaël Nossent  1 , Paul Haller  2 , Bernhard Jäger  2   3 , Kris G Vargas  2 , Johann Wojta  1   4   5 , Kurt Huber  2   3
Affiliations
Review

MicroRNAs as Regulators and Biomarkers of Platelet Function and Activity in Coronary Artery Disease

Stefan Stojkovic et al. Thromb Haemost. 2019 Oct.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Thromb Haemost. 2019 Oct;119(10):e1. doi: 10.1055/s-0040-1702204. Epub 2020 May 18. Thromb Haemost. 2019. PMID: 32422665 No abstract available.

Abstract

Microribonucleic acids (miRs) are small, noncoding ribonucleic acids (RNAs), which play an important role in the regulation of platelet function and activity. Several studies proposed a mechanistic role of platelet-related miRs in the pathophysiology of coronary artery disease (CAD) and atherothrombosis. Circulating, platelet-related miRs have been proposed as diagnostic, prognostic, as well as treatment response biomarkers in CAD and acute coronary syndrome (ACS). In this review, we summarize recent studies on the role of platelet-related miRs in the regulation of platelet function and activity. Furthermore, we review the studies investigating the role of platelet-related miRs as biomarkers in patients with CAD and ACS.

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Conflict of interest statement

None declared.