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Comment
. 2019 Oct;42(10):663-666.
doi: 10.1016/j.tins.2019.08.002. Epub 2019 Aug 14.

The Molecular Diversity of Vagal Afferents Revealed

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The Molecular Diversity of Vagal Afferents Revealed

Kristoffer L Egerod et al. Trends Neurosci. 2019 Oct.

Abstract

Using single-cell RNA sequencing (RNA-seq), Kupari and coworkers (Cell Rep., 2019) have generated a long sought-after molecular atlas of vagal afferents in the mouse. Vagal afferents were found to be organized into 24 subtypes, revealing a level of diversity that was not previously recognized.

Keywords: autonomic nervous system; single cell; transcriptomics; vagus nerve.

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