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. 1988 Aug;32(8):1269-70.
doi: 10.1128/AAC.32.8.1269.

Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys

V G Hemming  1 , G A Prince, W T London, P A Baron, R Brown, R M Chanock
Affiliations

Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys

V G Hemming et al. Antimicrob Agents Chemother. 1988 Aug.

Abstract

A human intravenous immunoglobulin preparation containing neutralizing antibodies to respiratory syncytial virus (RSV) was utilized for intratracheal and topical treatment of laboratory-induced RSV infections in owl monkeys (Aotus trivirgatus). Topically administered antibodies induced significant reductions in RSV shedding in the lower respiratory tract.

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