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Comparative Study
. 1988 Aug;32(8):1278-81.
doi: 10.1128/AAC.32.8.1278.

Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative

Affiliations
Comparative Study

Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative

S R Norrby et al. Antimicrob Agents Chemother. 1988 Aug.

Abstract

PD 127,391, a newly developed 4-quinolone chemically similar to ciprofloxacin, was studied in vitro by using agar and broth dilution and two inoculum sizes. PD 127,391 was found to be highly active against gram-negative aerobes, including Pseudomonas aeruginosa and other Pseudomonas spp. Its activity against gram-positive aerobes was better than that of ciprofloxacin.

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References

    1. Am J Med. 1985 Aug 9;79(2A):14-20 - PubMed
    1. J Med Chem. 1988 May;31(5):983-91 - PubMed
    1. J Antimicrob Chemother. 1986 Nov;18 Suppl D:1-20 - PubMed
    1. Rev Infect Dis. 1985 Jul-Aug;7 Suppl 3:S389-410 - PubMed

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