Lymphocyte markers, serum thymic factor and IgE in IgA deficiency

Abstract

Eleven patients having a selective IgA deficiency had very low T-cell percentages assessed by using E-rosettes, active E-rosetts and an anti-human anti-T-lymphocyte antigen serum. B-cells were normal or slightly decreased. IgE concentrations were often low. Patients with serum IgA under 50 IU/ml often had elevated serum IgE values and low T-cell percentages. Serum thymic factor dosages were correlated with the E-rosette assay.