Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Pimecrolimus

David Ahn  1 , Carolyn A. Robinson
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Pimecrolimus

David Ahn et al.
Free Books & Documents

Excerpt

Pimecrolimus cream is a prescription non-steroidal medication in the class of topical calcineurin inhibitors (TCIs). It is FDA-approved for the treatment of mild to moderate atopic dermatitis. This article will discuss the mechanism of action, administration, adverse effects, contraindications, monitoring, and theoretical toxicity associated with topical pimecrolimus that is pertinent to members of the healthcare team in the care of patients with atopic dermatitis and other inflammatory skin conditions.

PubMed Disclaimer

Conflict of interest statement

Disclosure: David Ahn declares no relevant financial relationships with ineligible companies.

Disclosure: Carolyn Robinson declares no relevant financial relationships with ineligible companies.

References

    1. Eichenfield LF, Tom WL, Berger TG, Krol A, Paller AS, Schwarzenberger K, Bergman JN, Chamlin SL, Cohen DE, Cooper KD, Cordoro KM, Davis DM, Feldman SR, Hanifin JM, Margolis DJ, Silverman RA, Simpson EL, Williams HC, Elmets CA, Block J, Harrod CG, Smith Begolka W, Sidbury R. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014 Jul;71(1):116-32. - PMC - PubMed
    1. El-Batawy MM, Bosseila MA, Mashaly HM, Hafez VS. Topical calcineurin inhibitors in atopic dermatitis: a systematic review and meta-analysis. J Dermatol Sci. 2009 May;54(2):76-87. - PubMed
    1. Murrell DF, Calvieri S, Ortonne JP, Ho VC, Weise-Riccardi S, Barbier N, Paul CF. A randomized controlled trial of pimecrolimus cream 1% in adolescents and adults with head and neck atopic dermatitis and intolerant of, or dependent on, topical corticosteroids. Br J Dermatol. 2007 Nov;157(5):954-9. - PubMed
    1. Lee GR, Maarouf M, Hendricks AK, Lee DE, Shi VY. Current and emerging therapies for hand eczema. Dermatol Ther. 2019 May;32(3):e12840. - PubMed
    1. Dattola A, Silvestri M, Bennardo L, Del Duca E, Longo C, Bianchi L, Nisticò S. Update of calcineurin inhibitors to treat inverse psoriasis: A systematic review. Dermatol Ther. 2018 Nov;31(6):e12728. - PubMed

Publication types

LinkOut - more resources