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Book

Embryology, Bowel

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Embryology, Bowel

Danielle J. Wilson et al.
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Excerpt

The bowel, which is composed of the small and large intestines, is vital to life as it absorbs nutrients necessary for all body functions. It is essential to understand the embryology of the bowel as errors in development serve as the basis for many congenital diseases.

The gastrointestinal tract divides into the foregut, midgut, and hindgut. The foregut forms the esophagus, stomach, pancreas, and the duodenum up to the ampulla of Vater. The midgut forms the distal duodenum, jejunum, ileum, cecum, ascending colon, and proximal two-thirds of the transverse colon. Finally, the hindgut forms the distal one-third of the transverse colon, descending colon, sigmoid colon, and the rectum. This article will focus on the development of the midgut and hindgut and explore developmental abnormalities that may occur during this process.

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Conflict of interest statement

Disclosure: Danielle Wilson declares no relevant financial relationships with ineligible companies.

Disclosure: Bruno Bordoni declares no relevant financial relationships with ineligible companies.

References

    1. Bhatia A, Shatanof RA, Bordoni B. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. May 1, Embryology, Gastrointestinal. - PubMed
    1. Spence JR, Lauf R, Shroyer NF. Vertebrate intestinal endoderm development. Dev Dyn. 2011 Mar;240(3):501-20. - PMC - PubMed
    1. Lenfestey MW, Neu J. Gastrointestinal Development: Implications for Management of Preterm and Term Infants. Gastroenterol Clin North Am. 2018 Dec;47(4):773-791. - PubMed
    1. Davis NM, Kurpios NA, Sun X, Gros J, Martin JF, Tabin CJ. The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery. Dev Cell. 2008 Jul;15(1):134-45. - PMC - PubMed
    1. Kluth D, Jaeschke-Melli S, Fiegel H. The embryology of gut rotation. Semin Pediatr Surg. 2003 Nov;12(4):275-9. - PubMed

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